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The Mechanisms Used by Human Papillomavirus to Escape the Host Immune Response


Wei Jiang, Ning-Li Li*
Shanghai Institute of Immunnology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
Abstract: Human papillomavirus (HPV) is a family of sexually transmitted, double-stranded DNA viruses which is associated with many different types of cancers including cervical, vaginal, head and neck, penile and anal cancer. The greatest risk factor for the development of cervical and other cancers that have been linked to the human papillomavirus (HPV) family is the persistence of the virus. The reason for persistence of the HPV is the virus can escape the host immunity. This review focuses on the advances in mechanisms used by HPV to escape the host immune system.


CSTR: 32200.14.cjcb.2008.01.0006