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The Roles of HSP70 and gp96 in Viral Infection
Liu-Meng Yang1, Hong-Liang Liu1,2, Yong-Tang Zheng1*
1Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China; 2Graduate School of Chinese Academy of Science, Beijing 100039, China
Abstract: Heat shock proteins (HSP)， a large protein family， are part of extraordinarily conserved during evolution and play diverse roles in cellular functions. HSPs are expressed in cells in response to a range of stimuli， including heat， mitogen and microbial/viral infection. HSP binding to viral antigen complex can enhance the antiviral immune. The review briefly introduces the roles of HSP70 and gp96 in the viral infection.
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