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Progress in nanos Gene


Chun-Dong Zhang, Min-Hui Pan*, Na Li, Zhi-Ya Sun, Juan Tan, Cheng Lu
Institute of Sericulture and Systems Biology, Southwest University, Chongqing 400716, China
Abstract: In many organisms, the regulations of the gene expression play important roles in the embryogenesis and postembryogenesis. nanos mRNA encodes a regulatory factor of translation, so the location and translation of maternal nanos mRNA in eggs are rigorous. In Drosophila melanogaster, maternal Nanos protein represses the translation of maternal hunchback mRNA in the posterior of the embryo to direct abdomen formation. The maternal Nanos protein is essential for the determination and migration of primordial germ cells and it is also required during the postembryogenesis. Here we review the nanos gene, including its localization of mRNA, control of translation, structure and function.


CSTR: 32200.14.cjcb.2009.01.0010