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Caspase and Central Nervous System Disease
SONG Ying, WEI Er Qing, CHEN Zhong*
Department of Pharmacology, Reasearch Centre for Brain and Intelligence, School of Medicine, Zhejiang University, Hangzhou 310031, China
Abstract: In recent years, considerable progress has been made in understanding the process of cell death. A character of many central nervous system (CNS) diseases is correlation with caspase. In this paper, we reviewed the important of caspase and the mechanisms of neuronal-cell death in CNS diseases. Meantime, we summarized the evidence concerned with apoptosis, and discussed the knowledge of therapeutic strategies.