Computational Analyses of MicroRNA Involved in Peroxisome Biogenesis and Proliferation

Abstract: MicroRNAs are small non-coding RNAs with 20?4 nucleotides in length and believed to be involved in a broad range of biological function， including cell proliferation， cell differentiation， cell apoptosis， development， responses to diseases and signal transduction， by base-pairing with complementary sites of target transcript to negatively regulate gene expression at the posttranscriptional level. Here we used a bioinformatics approach to identify conserved microRNAs which can complement with 3' untranslation region of target transcripts involved in peroxisome biogenesis and proliferation.

CSTR: 32200.14.cjcb.2009.02.0019