Growth Factors and Skin Wound Healing
HUANG Yuxiang, HE Xiaoyan*
Skin wound healing is a common clinical condition, including acute and chronic types. The wound repair process is usually divided into four phases: hemostasis, inflammation, cell proliferation and differentiation and tissue reconstruction, and the orderly conduct of each phase is the key to the success of wound repair. In the process of wound repair, growth factors play a crucial role, which is mainly reflected in six aspects: regulating vascular regeneration, regulating cell proliferation, migration and differentiation, influencing inflammation and oxidative stress, regulating collagen synthesis, regulating matrix synthesis, and regulating scar formation. Currently, research on the integrative role of growth factors in skin wound healing is relatively limited, and there is a relative paucity of available clinical treatments; therefore, exploring the link between growth factors and skin trauma healing can help to find and analyze new and effective therapeutic options. In this paper, the mechanism of action of growth factors in promoting skin healing and the advantages and disadvantages of clinically used wound healing materials are explored by means of graphical summarization and textual analysis, with the aim of providing certain references for future research related to skin wound healing and the development of new wound healing materials.
CN
EN