Recent Progress of Nanomedicine in Cancer Diagnosis and Therapy
YAO Shuo1#, LIU Dingxin1,2#, HAN Ge3, YANG Jiang1*
Despite significant progress in the diagnosis and treatment of cancer over the past few decades, cancer remains a major cause affecting human survival and health. Improving the early diagnosis and treatment outcomes of cancer holds crucial significance. In recent years, nanotechnology has rapidly advanced in the field of medicine, overcoming inherent limitations of traditional cancer diagnostic and therapeutic approaches and achieving notable success in clinical applications. Several representative drugs received drug approvals or are in clinical trial phases. However, nanomedicines still face challenges such as the complexity and heterogeneity of tumor biology, drug safety, and interactions at the nano-bio interface. This review elucidates recent applications of nanomedicine in cancer diagnosis and various treatment modalities, including chemotherapy, radiotherapy, phototherapy, chemodynamic therapy, immunotherapy, and combination therapy. The paper discusses challenges in clinical translation, production, and commercialization while offering a prospective outlook on future development opportunities and directions.
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