Research Progress on Leucine-Rich α2-Glycoprotein-1 in Inflammatory Diseases and Tumors
ZHAO Lingzhi, SONG Peipei, YOU Chongge*
LRG1 (leucine-rich α2-glycoprotein-1) is an important member of the leucine-repeat sequence protein family. LRG1 plays a key regulatory role in biological processes such as inflammation, angiogenesis, fibrosis, cell adhesion, apoptosis and cell activity. While various pathogenic mechanisms of LRG1 have been explored, its potential as a biomarker for diagnosis, prognosis and monitoring of diseases has also been extensively investigated. This article reviews the mechanisms of LRG1 in inflammatory diseases and tumors, aiming to provide a more comprehensive understanding of LRG1 and to realize the possibilities of LRG1 in clinical diagnosis and therapy.
CN
EN