Home > Browse Issues > Vol.31 No.2
The Progress in Research on the Physiological and Pathophysiological Role of Adiponectin
Chun-Yan Wan, Fen Liu, Zheng-Wei Fu*
College of Biological and Environment Engineering, Zhejiang University of Technology, Hangzhou 310014, China
Abstract: Adiponectin is an adipokine that is expressed specifically and abundantly in adipose tissue. The adiponectin receptors， AdipoR1 and AdipoR2， which mediate the antidiabetic metabolic actions of adiponectin. Adiponectin and adiponectin receptors represent potential versatile therapeutic targets to combat obesity-linked diseases characterized by insulin resistance. This review describes the characteristics， molecular mechanisms， and several important regulating factors of adiponectin and adiponectin receptors in insulin resistance， diabetes， and other metabolism diseases.
CN
EN