Home > Browse Issues > Vol.44 No.6
Advances of Research on Phosphatidylinositol Phosphatases Sac1
CHEN Hong1,2, HU Mandong2, CHEN Fangyan2, ZHAO Jingya2, LI Dingchen2, HAN Li2*
(1China Medical University, Shenyang 110122, China; 2Chinese PLA Center for Disease Control and Prevention, Beijing 100071, China)
Abstract:
PIPases (phosphatidylinositol phosphatases) Sac1 is an important group of phosphatases in volved in the metabolic pathway of phosphatidylinositol phosphatases, which can dephosphorylate phosphatidylinositol 4-phosphate and participate in a series of cellular functions such as inositol metabolism, actin cytoskeletal rearrangement and ATP transport. In this paper, the structure and function of phosphatidylinositol phosphatase Sac1 and its functions in mammalian cells, yeast cells and other eukaryotic cells are reviewed.
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