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Research Progress of Picornavirus and Autophagy
LI Juan, CHENG Anchun, WANG Mingshu*
(Avian Disease Research Center, College of Veterinary Medicine, Key Laboratory of Animal Diseases and Human Health of Sichuan Province, Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, International Joint Center for Animal Disease Prevention and Control in Sichuan Province, Chengdu 611130, China)
Abstract:
Autophagy is a self-protection mechanism of cells, which is the process of degrading and reusing damaged organelles and macromolecules through lysosomes. Recent studies have shown that picornaviruses promote their own replication by regulating autophagy. This paper summarizes the molecular mechanism of picornavirus inducing autophagy and the relationship between virus replication and autophagy, which provides a reference for the study of picornavirus and autophagy.
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