Home > Browse Issues > Vol.44 No.1
Neural Regulation of Adult Bone Marrow Hematopoiesis
YE Jinhui1, YIN Xiuxiu2, HU Linping1*, CHENG Tao1*
(1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China; 2Department of Intensive Care Unit, Emergency Medicine Research Institute, Tianjin First Center Hospital, Tianjin 300192, Chinaa)
Abstract:
HSCs (hematopoietic stem cells) can reconstitute the entire blood and immune systems. HSCs maintain their self-renewal and differentiation by intrinsic and extrinsic signals. Neural regulation, one of the three major systems for homeostasis, serves an important role in regulation of adult HSCs and their bone marrow microenvironment. Combined with the current research results, this paper reviews the role of the nervous system in the regulation of hematopoietic stem cell function and the maintenance of hematopoietic homeostasis.
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