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Research Progress on Abnormal Expression of miRNAs and Development of Cervical Cancer
YANG Xingye1, WANG Yu1, ZHOU Hui1, WAN Fusheng2*
(1The Second Clinical Medical College of Nanchang University, Nanchang 330006, China; 2Department of Biochemistry and Molecular Biology, Medical College of Nanchang University, Nanchang 330006, China)
Abstract:
CC (cervical cancer) is one of the diseases that seriously endanger women’s health, with high morbidity and mortality. miRNAs (microRNAs) are a class of small non-coding RNAs that regulate gene expression through post-transcriptional silencing. Abnormally expressed miRNAs are involved in the development of cervical cancer mainly by regulating cell cycle, apoptosis and various signaling pathways. In this paper, the research progress of miRNAs in the progress, diagnosis, treatment and prognosis of cervical cancer in recent years is reviewed to seek new ideas for the prevention and treatment of cervical cancer.
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