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The Role of Autophagy in Stroke and Its Possible Mechanism
Li Guangxiang, Zhang Pengyue*
Kunming University of Science and Technology, Kunming 650504, China
Abstract: Stroke is a serious neurological disease， the direct cause of which is the death and injury of neurons， so it is essential to save neurons for treating stroke. All the time， the death of brain neurons has been recognized as necrosis， apoptosis and autophagy， meanwhile necrosis and apoptosis cause the destruction of cells. However， recent studies have found that excessive autophagy does cause cell death， but a moderately activated autophagy could be crucial to the neuron survival.
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