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Progress of Osteogenetic Differentiation-mediated Proteins of Mesenchymal Stem Cells
Jiang Hengjun, Shen Yunyun, Zhu Kan, Li Minchao, Zeng Qunli*
The Key Laboratory Bioelectromagnetics, School of Medicine, Zhejiang University, Hangzhou 310058, China
Abstract: Mesenchymal stem cells (MSCs) are becoming ideal seed cells for clinical treatment of bone injuries due to their potential of osteogenesis. Osteogenetic differentiation of mesenchymal stem cells could be induced by the biological and chemical reagents and physical factors. During the differentiation， some ligands and transcription factors were involved in this process. In this review， we summed up studies of osteogenetic differentiation-mediated proteins of MSCs based on the literatures reported in recent 10 years in order to provide a basis and scientific guidance for the clinical application of mesenchymal stem cells.
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