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Targeted Therapy Strategies of Malignant Tumor Based on Cancer Stem Cells


Li Shanshan1, Wang Li2, Bian Yuhong1*
1Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China; 2Tianjin Second People’s Hospital, Tianjin 300192, China
Abstract: Cancer stem cells (CSCs) are involved in the formation, development and metastasis of tumor. Growing evidences indicated that therapies aiming at CSCs have been proven to be a new method for the treatment of malignant tumors. In order to give reference for the further studies, this paper summarized on CSCs and antitumor
    strategies aiming at CSCs such as CSCs surface markers, signal pathways, differentiation, microenvironment and immunotherapy.


CSTR: 32200.14.cjcb.2015.02.0020