Home > Browse Issues > Vol.29 No.2
The Origin and Biological Characteristics of Tumor Stem Cells
Jing Chen, Rong Cai, Cheng Qian*
Xin Yuan Institute of Medicine and Biotechnology, College of Life Sciences, Zhejiang Sci-tech University, Hangzhou 310018, China
Abstract: It is suspected that tumor stem cells give rise to tumorigenesis in that tumor stem cells share some biological characteristics with normal stem cells in self-renewal， proliferation & differentiation， expression of same superficial markers and strong drug-resistance. According to the similarity between tumor stem cells and normal stem cells， scientists explored a series of scientific experiment methods and established a number of experiment models in order to separate tumor stem cells from tumor tissues or tumor cell lines and discover the origin of tumor stem cells. This review comprehensively explains the latest studies on the origin and biological characteristics of tumor stem cells.
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