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Changes of Mitochondria during the Maturation of Oocytes
Shan Liu, Yuan Li, Zi-Jiang Chen*
Reproductive Medical Center of Shandong Provincial Hospital, Shandong University, Jinan 250021, China
Abstract: The maturation of oocyte is a complex progress. The nuclear and cytoplasmic maturation should be well-orchestrated in order to guarantee normal fertilization and further development. Mitochondria are the most important organelles in the cytoplasm and the distribution of which changes dramatically during maturation of oocyte. Meanwhile， the ATP generated by mitochondria is the main resource of energy for oocyte， zygote and embryo. Therefore， researches on the changes of distribution and function of mitochondria during maturation of oocyte will not only be helpful to understand reproductive physiology， but also provide new insights to resolve the problems to be faced with assisted reproductive technology.
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