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The Progress of Experimental Study on Stem Cell Therapy for Diabetic Foot
Guo Yongying1,2, Gao Huailin1,3,4*/
1Graduate School of Hebei Medical University, Shijiazhuang 050017, China; 2Yiling Medical Research Institute of Hebei Province, Key Laboratory of State Administration of Traditional Chinese Medicine (cardio-cerebral vascular network
Abstract: The diabetic foot (DF) is caused by diabetic vascular disease and/or neuropathy and infections as well as other factors， resulting in chronic progressive affected limb， micro vessel， and causing foot pain， skin ulcers or gangrene of limbs in deep. It is one of the serious complications of diabetes， occasionally causing amputation and even death. It is hard to obtain satisfactory effect， and clinical treatment is very difficult. Therefore， there is an urgent need to find a new treatment with fewer traumas， easier delivery， and good curative effect. Stem cells are capable of proliferation and differentiation into various kinds of cells. Their stronger plasticity brings new prospect for the treatment of diabetic foot. Currently， the stem cells attract attention of researchers worldwide. Here we review the progress on stem cell transplant therapy for the treatment of diabetic foot.
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