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Advances in the DMRT Gene Family Research


Zhang Yueyuan, Wang Changliu*
College of Life Sciences, Ludong University, Yantai 264025, China
Abstract: The DMRT gene family is a gene family related to sexual determination. Transcription factors encoded by DMRT genes have a conserved DM-domain linking to DNA by special zinc finger structures. The present studies of DMRT genes show that they mainly participate in sexual differentiation of embryo, developing of gonads and formation of gametes, and take part in other functions such as neurodevelopment. This paper reviews the advances in the DMRT gene family research, and expounds its structure, function and mechanism of action.


CSTR: 32200.14.cjcb.2013.11.0015