Hyphal Healing Mechanism in Filamentous Fungi

Abstract: Hyphal healing mechanism (HHM) plays an important role in the survival， development and lifestyle of filamentous fungi. Three HHMs had been discovered in filamentous fungi. In Pezizomycotina of Ascomycota，woronin bodies rapidly plug septal pores in response to hyphal damage. Septal pore cap (SPC) also acts as an emergency dolipore plugs to seal dolipores rapidly in damaged hyphae of Agaricomycotina (Basidiomycota).The hyphal healing process in Glomeromycota fungi (arbuscular mycorrhiza， AM) is divided into four steps. First，septa are produced at the cut-extremities of each section. Second， the first growing hyphal tip (GHT) appears from the cut-extremities of the section which is or not always the furthest one from the hyphal apex. Third， other GHTs are produced at the extremities of the other sections， and also multiple septa form in the apex side. Fourth， all the cut sections reconnect through the fusing of neighborhood GHTs. In this paper the research progress made in structural biology， systems biology and genetics associated with HHM in filamentous fungi were discussed.

CSTR: 32200.14.cjcb.2013.04.0022