Home > Browse Issues > Vol.34 No.10
DNA Damage Response and SUMO Modification
Jiang Huadong, Li Yu*
School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China
Abstract: DNA damage can be produced widely in our body by physical and/or chemical factors. Therefore， in order to maintain the genomic integrity， DNA must be protected from DNA damage and repaired correctly by forming accurate mechanism if DNA damage happened. SUMOylation has multiple biological functions like other post-translation modification. Emerging evidence has showed that SUMOs play vital roles in DNA damage repair. This review focuses on the newly research about DNA damage， SUMOylation and the relationship between them and provides a complete introducing and summarization.
CN
EN