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The Function of CCK and CCK Receptors during Gallstone Formation
Yang Yang, Qu Qiang*, Wei Jinhua, Liu Wei, Hong Tao, He Xiaodong
Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, CAMS, Beijing 100730, China
Abstract: Cholecystokinin (CCK) is the most important postprandial hormone inducing gallbladder contraction. It has great influence on the change of gallbladder motility by binding to CCK receptors (CCK-R). More and more researches reveal that the defect of gallbladder motility facilitates gallstone formation. This review focuses on the influence of CCK and CCK receptors on gallbladder motility and gallstone formation.
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