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The Effect of GnRH Impulse Mode on FSH


Xin Wang1,2, Jian-Hua Tan3, Xiao-Ping Lai2, Zhong-Hai Wan3*, Xu-Bin Wei4*
1Animal Science College of Qingdao Agricultural University, Qingdao 266109, China; 2 Traditional Chinese Medical Academy of Guangzhou University of Chinese Medicine, Guangzhou 510006, China; 3 Institute of Military Veterin
Abstract: This article aims to research the influence of GnRH impulse mode on the secretion of FSH. The stimulation experiment of GnRH at different frequencies and with different amplitude lasted 24 h, and then the secretory volume of FSH was detected. The result shows the secretory volume of FSH reaches the top when the frequency of GnRH impulse is 120 min and the vibration amplitude of it is 20 nmol/L, moreover, with the hurrying up or the stepping down of the frequency of GnRH stimulation, the secretion of FSH is both reducing gradually. So, GnRH impulse frequency itself is a regulation signal, and the different impulse frequencies of GnRH have clearly different influence on the expression of FSH. In the condition of the same vibration amplitude, when the cells are stimulated by impulse at low frequency (at the interval of 120 min), the secretion of FSH reaches the top.


CSTR: 32200.14.cjcb.2011.03.0008