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PBEF/Visfatin/Nampt -Adipikines， Enzyme or Proinflammatory?
Hong-Yan Zhang1,2, Li-Zhi Lu2, Xiao-Ling Liu1*
1Department of Ophthalmology and Optometry, School of Wenzhou Medical Collage, Wenzhou 325000, China;2Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China
Abstract: Adipokines are bioactive peptides， secreted by adipose tissue， which are considered to be important factors of metabolism. PBEF/Visfatin/Nampt has been proposed to be a novel adipokine with insulin mimetic effect in 2005. Although the precise mechanisms underlying the beneficial effects on insulin sensitivity remain unknown， understanding this new exciting world of adipocytokines will be of importance in the development of novel therapeutic approaches for obesity-related disorders.
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