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Research Progress on the Toxicity of Microcystins to Mulitiple Target Organs
Ye Guanchen1, Wang Yiru1, Xu Lihong2*
(1Department of Dentistry, School of Medicine, Zhejiang University, Hangzhou 310058, China; 2 Department of Biochemistry, School of Medicine, Zhejiang University, Hangzhou 310058, China)
Abstract:
Microcystin is a kind of monocyclic heptapeptide toxin produced mainly by microcystis. In recent years, studies have shown that microcystin has embryotoxicity and reproductive toxicity, which can lead to embryo death, deformity or retardation, affecting the level of reproductive hormones and having negative effects on the reproductive system. In addition, microcystin also jeopardise the nervous system and immune system by the mechanisms of inducing apoptosis, oxidative stress and mitochondrial dysfunctions. This paper summarizes the latest research progress mentioned above and looks forward to the future research direction.
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