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Cardiac Organoids: Applications in Research on Cardiovascular Development and Disease-Current Status and Future Perspectives
LIANG Yiyun1,2, MENG Qinghang1,2*
(1Greater Bay Area Institute of Precision Medicine (Guangzhou), Guangzhou 511458, China; 2School of Life Sciences, Fudan University, Shanghai 200438, China)
Abstract:
Cardiovascular diseases are major global public health challenges. Cardiac organoid technology, as an emerging bioengineering approach, provides novel tools by mimicking cardiovascular development and disease mechanisms. This review traces the evolution of cardiac organoids and highlights their applications in studying development and disease. While challenges regarding functionality, ethics, and costs remain, the integration of novel methodologies offers promising prospects. Future research directions are also discussed to inform this rapidly advancing field.
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