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Research Advances of Maternal Obesity and Reproductive Health


HE Yu, TANG Shoubin, HAN Longsen, WANG Qiang*

(State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing 211166, China)
Abstract:

With an escalating global epidemic of obesity, the prevalence of obesity among reproductive women continues to rise, adversely impacting female reproductive health. It has been widely reported that maternal obesity has profound effects on oocyte and embryo qualities, as well as fetal and offspring development. This article aims to elucidate the influence of maternal obesity on reproductive health from three aspects: oocyte quality, embryo and fetal development, offspring health, and proposes potential interventions by integrating reported mechanisms to improve poor reproductive performances and offspring disease caused by maternal obesity, and consequently promoting eugenics.