Biological Role and Functional Mechanism of Baicalin

YANG Xianguang^1,2*, SUN Gege¹, DING Cuihong¹, WEN Pingping¹

(¹College of Life Science, Henan Normal University, Xinxiang 453007, China; ²State Key Laboratory Cultivation Base for Cell Differentiation Regulation, Henan Normal University, Xinxiang 453007, China)

Abstract:

Baicalin is a biologically active flavonoid compound, which is the main active ingredient of the perennial herb Scutellaria baicalensis. At present, relevant cell experiments and animal experiments have shown that baicalin has a variety of biological functions. This paper reviews the latest literatures at home and abroad in recent years. The functional studies and mechanism of baicalin on liver protection, brain protection, antioxidant, antidiabetes, anti-tumor, as well as its effect on microRNA are reviewed. This study provides a new reference for the further development and clinical application of baicalin.