Advances in Research on the Structure and Biological Function of Actin

LIU Ruijiao, Abdulrahman A.A. Amer, GAO Xinghua, CHEN Hongduo, QI Ruiqun*

(The First Hospital of China Medical University, Ministry of Education Key Laboratory of Immunodermatology, Shenyang 110001, China)

Abstract:

Actin is one of the most abundant proteins in eukaryotes, distributed throughout the cell. Microfilaments are formed by the polymerization of actin, which are involved in numerous biological processes of cells. With the development of the study on the biological characteristics of actin, its application in molecular biology has attracted much attention. In this paper, the structure, assembly dynamics and biological functions of actin are reviewed from the molecular level.