Research Progress of GSK-3β in the Regulation of the Pathological Process of Ischemic Stroke

As one of the most important kinases in the body, GSK-3β (glycogen synthase kinase-3β) is widely involved in the pathological processes of ischemic stroke. Therefore, correctly understanding the function of GSK-3β after stroke and making use of it are important for seeking ways to reduce tissue damage and improve nerve function to improve the treatment of stroke. In this paper, the mechanisms of GSK-3β in regulating oxidative stress, inflammation, autophagy and apoptosis in ischemic stroke are reviewed, which provides research directions and potential treatment targets for ischemic stroke.