Dynamics of Nuclear Pore Complex Organization

Hui Guan, Yan-Ping Zhang, Jing Song, Bao-Chang Zhu*
(College of Life Science, Capital Normal University, Beijing 100037, China)

Abstract Nuclear pores are only gates for all macromolecules that traffic between the nucleus and the cytoplasm. The nuclear pore complexes consist of varied proteins that always are in dynamic assembly during the whole life of the cells. Present article elucidate dynamics of nuclear pore complexes organizations that alter properties of nuclear pores in transportation and, ultimately, the cellular functions.

Key words nuclear pore complexes; nucleoporin; dynamic organization; nuclear transport

Received: November 23, 2005 Accepted: March 13, 2006
This work was supported by the National Natural Science Foundation of China (No.30270197, No.39970553)
*Corresponding author. Tel: 86-10-68903623, E-mail: baochang@mail.cnu.edu.cn