Vol.26 No.3£¨2004 June£©£º216-220 Molecular Mechanisms of AMPA Receptor Endocytosis ZHENG Chan Ying, LUO Jian Hong*, ZHAO Hui £¨School of Medical, Zhejiang University, Hangzhou 310006, China£© Abstract: There are two kinds of AMPA receptor endocytosis: constitutive endocytosis and activity-dependent endocytosis. AMPA receptors endocytosis means more than the end of the receptor's activity. Some important signal transduction of AMPA receptors are mediated by this process. It is associated with activity-dependent endocytosis This article reviewed the process and function of AMPA receptor endocytosis, and the molecular mechanism in which the trigger, regulation, fate of the activity-dependent endocytosis of AMPA receptors undergo. Key words: AMPA receptor; endocytosis; activity-dependent endocytosis *Corresponding author, E-mail: luojianhong@zju.edu.cn |