Vol.26 No.2£¨2004 April£©£º139-144

RNA Polymerase ¢ò Transcription Elongation Factors

LI Fen1, LU Jun*, HUANG Bai Qu

£¨Institute of Genetics and Cytology, Northeast Normal University, Changchun, Jilin 130024, China£©

Abstract: When RNA polymerase¢òpasses through the coding region of a gene, it must overcome various kinds of obstacles including the tightly wrapped nucleosomes. Mechanisms to deal with these obstacles clearly exist in cells, because transcription through chromatin is very efficient in vivo. An increasing number of different categories of elongation factors that assist polymerase¢òin this process have been identified by genetical and biochemical researches. Here we review the advances in studies of elongation factors according to their types and functions.

Key words: RNA polymerase ¢ò; elongation factor; transcription elongation

1 Current address: Henan Normanl University, Xinxiang 135002, China
*Corresponding author, E-mail: luj809@nenu.edu.cn