Vol.26 No.1（2004 February）：10-14

SUMO, a Ubiquitin-related Protein

YE Xiao Feng, WU Qiao*

（Key Laboratory of the Ministry of Education for Cell Biology and Tumor Cell Engineering,School of Life Sciences, Xiamen university, Xiamen 361005, China）

Abstract: Sumo (small ubiquitin-related modifier) is one of the ubiquitin-related proteins and resembles ubiquitin's ability to be reversibly ligand to other proteins. Unlike ubiquitin induces protein degradation, sumoylation regulates protein/protein interaction, localization ,and stability. Here we show more details about sumo in class, structure, ligation pathway and biological function.

Key words: SUMO; Sumoylation

*Corresponding author, E-mail: xgwu@xmu.edu.cn